Achilles Had Only 2 Heels
















Recently, I came across the headline “Scientists Find Achilles’ Heel of Cancer Cells”, describing the discovery of a histone deactylase (HDAC11) as a novel target for cancer therapies. I was irritated by the metaphor of Achilles’ heel, because it implied that this was the lone vulnerability of cancer. I was also embarrassed by the fact that I used the same metaphor for the press release describing our work earlier this year showing that mitochondrial network structure can be targeted in cancer. I decided to google the expressions “Achilles’ heel” and “cancer”. It turns out that every year, numerous press releases and news articles claim that researchers have finally identified the “Achilles’ heel” of cancer. In Greek mythology, Achilles only had two feet and thus two heels; only one of the two heels was vulnerable. So how can it be that hundreds of researchers have found the Achilles’ heel of cancer? Apparently, I am not the only one who has used this metaphor inappropriately and it begs the question, whether we should even be using it at all. When I was a child, Gustav Schwab‘s “Sagen des klassischen Altertums” was one of my favorite books. His gripping narrative of the ancient Greek myths has also been translated from German into English and is available as “Gods and Heroes of Ancient Greece”. It was in this book that I first encountered the legend of Achilles and the story of the Trojan War, originally relayed by the Greek poet Homer in his great epic “The Illiad“. Achilles was the son of the sea-goddess (nymph) Thetis and King Peleus and was known for his great strength and skills in battle, but I could find nothing heroic in this demigod Achilles. Even though I loved Schwab’s narration, I despised Achilles. He vacillated between fits of rage and episodes of prolonged sulking. He was rude, arrogant and violent – Anakin Skywalker on steroids. I was especially horrified by how Achilles tied the body of his enemy Hector to his chariot and dragged it around, in order to humiliate the deceased and inflicting great psychological pain on Hector’s family. Basically, Achilles was a jerk; but according to the diagnostic classification of the American Psychiatric Association, Achilles may just have had IED (intermittent explosive disorder). When Achilles was a baby, his mother Thetis stuck him in a special flame to make him invulnerable. She was interrupted by Achilles’ father, who was shocked by what he perceived as poor parenting skills shown by Thetis. The interruption prevented Thetis from making her son completely invulnerable, which is why one of Achilles’ heels remained vulnerable. Later on in the legend, this vulnerable heel is where the Greek god Apollo directs his arrow and this injury ultimately results in Achilles’ demise. I remember the relief I experienced when I first read about Achilles’ death. It was karma – he deserved to die, considering all the pain and suffering that he had caused. I also remember that I was confused by the whole invulnerability aspect of the story. In a different part of the legend, his mother Thetis helps him obtain a special armor to protect his body. If nearly all of his body was already invulnerable, why would he need such a special armor? Wouldn’t he just need a special kind of Band-Aid to cover his one vulnerable heel? But then again, these were Greek gods and goddesses and they may have had different ways of approaching problems. Perhaps the special armor was extra insurance, just like people whose personal auto insurance covers rental cars but they still get suckered into buying additional rental car insurance at the airport. Later on, I found out the Schwab had combined multiple Achilles legends. The story of Achilles being invulnerable everywhere except for his heel and Achilles’ death are not part of Homer’s Illiad. It was long after Homer that the heel story became an integral part of the Achilles legend. In one version, Thetis did not place Achilles in a flame but instead dipped him in the magical River Styx. She held him by the heel of his foot, which is why he remained vulnerable in that one area. I am not sure that I would have held my son by the heel of all places, while dipping him into a magical river. Then again, I am not a Greek god. It also begs the question why Thetis did not dip him in a second time to make sure that the previously dry heal now also became invulnerable. In one narration, it was not Apollo who shot the arrow, but the Trojan prince Paris and Apollo merely directed the arrow into Achilles’ heel, possibly because Paris was not a very good shot. Even though the heel story and Achilles’ death or not part of the Illiad, it is difficult to envision the Achilles legend without it. The idea that even strong, arrogant entities remain vulnerable is very comforting. This may explain why this aspect of the legend is so popular and why it has given rise to the commonly used metaphor of the “Achilles’ heel” to describe lone vulnerable spots. Especially when describing cancer, the metaphor seems very apt. One can easily envision a growing tumor as an Achilles – aggressive and apparently invincible. When one identifies a gene or protein that can prevent tumor growth and or even kills the tumor, it is easy to succumb to using the “Achilles’ heel” metaphor. The problem with using this metaphor is that Achilles only had one single vulnerable heel. If a researcher claims to have found an Achilles’ heel, it not only implies that it is “one” area of vulnerability of the cancer, but that it is the “only” area of vulnerability. Most researchers who work with cancer cells know that there are many different mechanisms by which cancer growth can be slowed down. There is no single vulnerable pathway that can stop all cancer progression. Therefore, when researchers use this expression, they probably just like to convey the image of the powerful Achilles being brought to his knees by a single arrow. They do not want to claim that they have found the ultimate weapon to fight cancer. However, this metaphor inadvertently does imply that the described method is the only way to arrest the tumor. This is not only a gross over-simplification, but plain wrong. Someone who is not familiar with the complexities of cancer biology and reads a press release containing this metaphor may take this to mean that the sole vulnerability of cancer has been identified. Mythology and literature can be very inspiring for scientists and it is tempting to use powerful literary or mythological metaphors when communicating science, but one also needs to think about what these metaphors truly represent. Especially metaphors that oversimplify scientific findings or convey a false sense of certainty should be used avoided. When I think about research, two other Greek legends come to mind: The legend of Sisyphus and the Odyssey. Every day, Sisyphus rolled a rock up a mountain and then had to watch how it would roll back down again. This was his punishment decreed by the Greek gods. It reminds me of a lot of experiments that we scientists perform. When we feel that we are getting close solving a scientific problem we sometimes realize that we have to start all over again. Similarly, Odysseus’ long and exhausting journey is also a metaphor that appropriately characterizes a lot of real-life scientific research. Odysseus did not know if and when he would ever reach his destination, and this is how many of us conduct our research. I googled “Odyssey” and “cancer” to see if I could find news articles that allude to the scientific Odyssey of cancer research. To my surprise, I did find a number of articles, but these were not descriptions of scientific “Odysseys”. They were reports of cancer patients who described how they had undergone numerous different cancer treatments, often with little improvement. I realize that it is easier to market scientific ideas with a simplistic Achilles metaphor than to point out that science is long-winded and at times disorienting journey, similar to the Odyssey. But if we do want to use metaphors, we should probably use ones that appropriately convey the complexity and beauty of science.  


Follow Scientific American on Twitter @SciAm and @SciamBlogs. Visit ScientificAmerican.com for the latest in science, health and technology news.
© 2012 ScientificAmerican.com. All rights reserved.













Health News Headlines – Yahoo! News



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'Evolved': Hannity, Boehner say GOP should tackle immigration reform

Sean Hannity (AP)Well, that was fast.


Just two days after President Barack Obama sailed to re-election over Mitt Romney, boosted by more than 70 percent of the Latino vote, some Republicans are striking a new tone on illegal immigration.


Conservative Fox News and radio host Sean Hannity said Thursday that his views on immigration have "evolved." Hannity continued:


We've gotta get rid of the immigration issue altogether. It's simple for me to fix it. I think you control the border first, you create a pathway for those people that are here, you don't say you gotta go home. And that is a position that I've evolved on. Because you know what—it just—it's gotta be resolved. The majority of people here—if some people have criminal records you can send 'em home—but if people are here, law-abiding, participating, four years, their kids are born here ... first secure the border, pathway to citizenship ... then it's done. But you can't let the problem continue. It's gotta stop.


Meanwhile, in an interview with ABC News' Diane Sawyer, House Speaker John Boehner said he is "confident" the two parties can agree to a deal on immigration.


"This issue has been around far too long," Boehner said. "A comprehensive approach is long overdue, and I'm confident that the president, myself, others can find the common ground to take care of this issue once and for all."


Just two years ago, Boehner said it was worth considering amending the U.S. Constitution to end birthright citizenship, because he said it might discourage people from illegally crossing the border.


Former Secretary of State Condoleezza Rice, who supports immigration reform, said on CBS on Friday that Republicans had sent "mixed messages" about immigration. "On the immigration issue, which turned out to be very important, and some issues about women, too, some mixed messages were sent," she said.


The party has been searching for answers about why Mitt Romney lost what seemed like a very winnable election. Many within the party have pointed to the GOP's demographics problem: Romney lost every group except for white voters, which is a shrinking portion of the electorate. Latinos this year made up 10 percent of all voters, according to the national exit poll, a share that will only grow each election. Like other groups, Latino voters care most about jobs and the economy, but 35 percent of them listed immigration reform as their top issue in a poll conducted by Latino Decisions.


Latino voter and advocacy groups have said they expect both Obama and congressional Republicans to work together to pass immigration reform in 2013.


Eliseo Medina, secretary-treasurer of the Service Employees International Union, told reporters that Latino voters had sent a message to Obama. "We expect leadership on comprehensive immigration reform in 2013," he said. "To both sides we say: 'No more excuses.'"


Read More..

Call me JackSUN, says singer Jermaine
















LOS ANGELES (Reuters) – Jackson 5 singer Jermaine Jackson has petitioned to change his name, according to court documents filed earlier this week in Los Angeles.


The older brother of pop stars Michael and Janet Jackson, Jermaine wants to change his famous last name to Jacksun for “artistic reasons.”













Asked why Jermaine wanted to change his name, his attorney Bret D. Lewis, who filed the petition on Jackson’s behalf, told Reuters “If Prince and P Diddy can do it, why can’t and shouldn’t Jermaine?”


If all goes to plan, Jackson’s name will officially change following a court hearing set for February 22.


Jermaine, 57, and brothers Jackie, Marlon and Tito are currently in Europe on a Unity Tour, under the name The Jacksons, performing hits made famous by the Jackson 5 along with a tribute to their late sibling Michael.


Jermaine Jackson unofficially adopted the name Mohammad Abdul Aziz after converting to Islam in 1989.


(Reporting By Eric Kelsey, editing by Jill Serjeant and Bernard Orr)


Music News Headlines – Yahoo! News



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11,000 flee Syria in huge one-day exodus

DEAR ABBY: My brother lost his wife, the love of his life, three years ago. He has three children. His oldest, a 25-year-old daughter, "Jenny," told him that "when you marry, it is for life." She has threatened that if he dates someone or sees anyone, she will be out of his life and he won't be able to see his future grandchildren. (Jenny is getting married next summer.)My brother is very upset. He wants to settle this argument before she is married. He hasn't dated anyone, but feels she shouldn't be trying to control his life. Please help, Abby. ...
Read More..

Achilles Had Only 2 Heels
















Recently, I came across the headline “Scientists Find Achilles’ Heel of Cancer Cells”, describing the discovery of a histone deactylase (HDAC11) as a novel target for cancer therapies. I was irritated by the metaphor of Achilles’ heel, because it implied that this was the lone vulnerability of cancer. I was also embarrassed by the fact that I used the same metaphor for the press release describing our work earlier this year showing that mitochondrial network structure can be targeted in cancer. I decided to google the expressions “Achilles’ heel” and “cancer”. It turns out that every year, numerous press releases and news articles claim that researchers have finally identified the “Achilles’ heel” of cancer. In Greek mythology, Achilles only had two feet and thus two heels; only one of the two heels was vulnerable. So how can it be that hundreds of researchers have found the Achilles’ heel of cancer? Apparently, I am not the only one who has used this metaphor inappropriately and it begs the question, whether we should even be using it at all. When I was a child, Gustav Schwab‘s “Sagen des klassischen Altertums” was one of my favorite books. His gripping narrative of the ancient Greek myths has also been translated from German into English and is available as “Gods and Heroes of Ancient Greece”. It was in this book that I first encountered the legend of Achilles and the story of the Trojan War, originally relayed by the Greek poet Homer in his great epic “The Illiad“. Achilles was the son of the sea-goddess (nymph) Thetis and King Peleus and was known for his great strength and skills in battle, but I could find nothing heroic in this demigod Achilles. Even though I loved Schwab’s narration, I despised Achilles. He vacillated between fits of rage and episodes of prolonged sulking. He was rude, arrogant and violent – Anakin Skywalker on steroids. I was especially horrified by how Achilles tied the body of his enemy Hector to his chariot and dragged it around, in order to humiliate the deceased and inflicting great psychological pain on Hector’s family. Basically, Achilles was a jerk; but according to the diagnostic classification of the American Psychiatric Association, Achilles may just have had IED (intermittent explosive disorder). When Achilles was a baby, his mother Thetis stuck him in a special flame to make him invulnerable. She was interrupted by Achilles’ father, who was shocked by what he perceived as poor parenting skills shown by Thetis. The interruption prevented Thetis from making her son completely invulnerable, which is why one of Achilles’ heels remained vulnerable. Later on in the legend, this vulnerable heel is where the Greek god Apollo directs his arrow and this injury ultimately results in Achilles’ demise. I remember the relief I experienced when I first read about Achilles’ death. It was karma – he deserved to die, considering all the pain and suffering that he had caused. I also remember that I was confused by the whole invulnerability aspect of the story. In a different part of the legend, his mother Thetis helps him obtain a special armor to protect his body. If nearly all of his body was already invulnerable, why would he need such a special armor? Wouldn’t he just need a special kind of Band-Aid to cover his one vulnerable heel? But then again, these were Greek gods and goddesses and they may have had different ways of approaching problems. Perhaps the special armor was extra insurance, just like people whose personal auto insurance covers rental cars but they still get suckered into buying additional rental car insurance at the airport. Later on, I found out the Schwab had combined multiple Achilles legends. The story of Achilles being invulnerable everywhere except for his heel and Achilles’ death are not part of Homer’s Illiad. It was long after Homer that the heel story became an integral part of the Achilles legend. In one version, Thetis did not place Achilles in a flame but instead dipped him in the magical River Styx. She held him by the heel of his foot, which is why he remained vulnerable in that one area. I am not sure that I would have held my son by the heel of all places, while dipping him into a magical river. Then again, I am not a Greek god. It also begs the question why Thetis did not dip him in a second time to make sure that the previously dry heal now also became invulnerable. In one narration, it was not Apollo who shot the arrow, but the Trojan prince Paris and Apollo merely directed the arrow into Achilles’ heel, possibly because Paris was not a very good shot. Even though the heel story and Achilles’ death or not part of the Illiad, it is difficult to envision the Achilles legend without it. The idea that even strong, arrogant entities remain vulnerable is very comforting. This may explain why this aspect of the legend is so popular and why it has given rise to the commonly used metaphor of the “Achilles’ heel” to describe lone vulnerable spots. Especially when describing cancer, the metaphor seems very apt. One can easily envision a growing tumor as an Achilles – aggressive and apparently invincible. When one identifies a gene or protein that can prevent tumor growth and or even kills the tumor, it is easy to succumb to using the “Achilles’ heel” metaphor. The problem with using this metaphor is that Achilles only had one single vulnerable heel. If a researcher claims to have found an Achilles’ heel, it not only implies that it is “one” area of vulnerability of the cancer, but that it is the “only” area of vulnerability. Most researchers who work with cancer cells know that there are many different mechanisms by which cancer growth can be slowed down. There is no single vulnerable pathway that can stop all cancer progression. Therefore, when researchers use this expression, they probably just like to convey the image of the powerful Achilles being brought to his knees by a single arrow. They do not want to claim that they have found the ultimate weapon to fight cancer. However, this metaphor inadvertently does imply that the described method is the only way to arrest the tumor. This is not only a gross over-simplification, but plain wrong. Someone who is not familiar with the complexities of cancer biology and reads a press release containing this metaphor may take this to mean that the sole vulnerability of cancer has been identified. Mythology and literature can be very inspiring for scientists and it is tempting to use powerful literary or mythological metaphors when communicating science, but one also needs to think about what these metaphors truly represent. Especially metaphors that oversimplify scientific findings or convey a false sense of certainty should be used avoided. When I think about research, two other Greek legends come to mind: The legend of Sisyphus and the Odyssey. Every day, Sisyphus rolled a rock up a mountain and then had to watch how it would roll back down again. This was his punishment decreed by the Greek gods. It reminds me of a lot of experiments that we scientists perform. When we feel that we are getting close solving a scientific problem we sometimes realize that we have to start all over again. Similarly, Odysseus’ long and exhausting journey is also a metaphor that appropriately characterizes a lot of real-life scientific research. Odysseus did not know if and when he would ever reach his destination, and this is how many of us conduct our research. I googled “Odyssey” and “cancer” to see if I could find news articles that allude to the scientific Odyssey of cancer research. To my surprise, I did find a number of articles, but these were not descriptions of scientific “Odysseys”. They were reports of cancer patients who described how they had undergone numerous different cancer treatments, often with little improvement. I realize that it is easier to market scientific ideas with a simplistic Achilles metaphor than to point out that science is long-winded and at times disorienting journey, similar to the Odyssey. But if we do want to use metaphors, we should probably use ones that appropriately convey the complexity and beauty of science.  


Follow Scientific American on Twitter @SciAm and @SciamBlogs. Visit ScientificAmerican.com for the latest in science, health and technology news.
© 2012 ScientificAmerican.com. All rights reserved.













Health News Headlines – Yahoo! News



Read More..

Icahn says has mulled Netflix takeover, no decision made
















(Reuters) – Activist investor Carl Icahn, who holds an almost 10 percent stake in Netflix, said on Thursday he has considered a hostile takeover bid for Netflix, but it was uncertain he stood a chance of acquiring the Internet streaming service.


Asked by TV network CNBC whether he would “go hostile” on Netflix, Icahn said, “The thought had certainly entered my mind. I have to admit I think about it, but we haven’t made that decision.”













While Icahn said a hostile takeover was “certainly an alternative,” he downplayed the possibility several times. He added that he would not be able to pay as much for Netflix as a “synergistic buyer” looking to acquire an Internet movie and TV subscription service.


Netflix has been the subject of periodic acquisition speculation, with potential names tossed around from Microsoft Corp to Amazon.com Inc.


Icahn last month disclosed he had amassed control of 9.98 percent of Netflix shares. Most of his purchases were in the form of call options that expire in September 2014. The billionaire, who is known for shaking up corporate management, has said Netflix was undervalued and an attractive acquisition target for a number of companies.


Netflix has since adopted a poison pill defense to prevent a hostile takeover, a move that Icahn on Thursday called “reprehensible.”


A Netflix spokesman did not immediately respond to a request for comment on Icahn’s remarks.


(Reporting By Liana B. Baker in New York; Additional reporting by Katya Wachtel and Sam Forgione in New York and Lisa Richwine in Los Angeles; Editing by Leslie Adler)


Internet News Headlines – Yahoo! News



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Assad says will live and die in Syria
















DOHA (Reuters) – President Bashar al-Assad said he would “live and die” in Syria and warned that any Western invasion to topple him would have catastrophic consequences for the Middle East and beyond.


Assad’s defiant remarks coincided with a landmark meeting in Qatar on Thursday of Syria’s fractious opposition to hammer out an agreement on a new umbrella body uniting rebel groups inside and outside Syria, amid growing international pressure to put their house in order and prepare for a post-Assad transition.













The Syrian leader, battling a 19-month old uprising against his rule, appeared to reject an idea floated by British Prime Minister David Cameron on Tuesday that a safe exit and foreign exile for the London-educated Assad could end the civil war.


“I am not a puppet. I was not made by the West to go to the West or to any other country,” he told Russia Today television in an interview to be broadcast on Friday. “I am Syrian; I was made in Syria. I have to live in Syria and die in Syria.”


Russia Today’s web site, which published a transcript of the interview conducted in English, showed footage of Assad speaking to journalists and walking down stairs outside a white villa. It was not clear when he had made his comments.


The United States and its allies want the Syrian leader out, but have held back from arming his opponents or enforcing a no-fly zone, let alone invading. Russia has stood by Assad.


The president said he doubted the West would risk the global cost of intervening in Syria, whose conflict has already added to instability in the Middle East and killed some 38,000 people.


“I think that the price of this invasion, if it happened, is going to be bigger than the whole world can afford … It will have a domino effect that will affect the world from the Atlantic to the Pacific,” the 47-year-old president said.


“I do not think the West is going in this direction, but if they do so, nobody can tell what is next.”


QATAR, TURKEY CHIDE OPPOSITION


Backed by Washington, the Doha talks underline Qatar’s central role in the effort to end Assad‘s rule as the Gulf state, which funded the Libyan revolt to oust Muammar Gaddafi, tries to position itself as a player in a post-Assad Syria.


Qatari Prime Minister Hamad bin Jassim Al Thani urged the Syrian opposition to set its personal disputes aside and unite, according to a source inside the closed-door session.


“Come on, get a move on in order to win recognition from the international community,” the source quoted him as saying.


Turkish Foreign Minister Ahmed Davutoglu delivered a similar message, saying, according to the source: “We want one spokesman not many. We need efficient counterparts, it is time to unite.”


An official text of a speech by Qatari Foreign Minister Khalid Mohamed al-Attiyah showed he told the gathering: “The Syrian people awaits unity from you, not divisions … Your agreement today will prove to the international community that there is a unity … and this will reflect positively in the international community’s stance towards your fair cause.”


Across Syria, more than 90 people were killed in fighting on Thursday, the Syrian Observatory for Human Rights said.


In Turkey’s Hatay border province, two civilians, a woman and a young man, were wounded by stray bullets fired from Syria, according to a Turkish official. Turkish forces increased their presence along the frontier, where officials have said they might seek NATO deployment of ground to air missiles.


Syria poses one of the toughest foreign policy challenges for U.S. President Barack Obama as he starts his second term.


International rivalries have complicated mediation efforts. Russia and China have vetoed three Western-backed U.N. Security Council resolutions that would have put Assad under pressure.


Syria’s conflict, pitting mostly Sunni Muslim rebels against forces dominated by Assad’s Alawite minority, whose origins lie in Shi’ite Islam, has fuelled sectarian tensions across the Middle East. Sunni Arab countries and Turkey favor the rebels, while Shi’ite Iran backs Assad, its main Arab ally.


“VICIOUS CIRCLE”


The main opposition body, the Syrian National Council (SNC), has been heavily criticized by Western and Arab backers of the revolt as ineffective, run by exiles out of touch with events in Syria, and under the sway of the Islamist Muslim Brotherhood.


British Foreign Minister William Hague said London would now talk to rebel groups inside Syria, after U.S. Secretary of State Hillary Clinton last week criticized the SNC and called for a new opposition body to include those “fighting and dying”.


But the plan for a body that could eventually be considered a government-in-waiting capable of winning foreign recognition and therefore more military backing ran into trouble almost as soon as it was proposed by SNC member Riyad Seif.


The meeting has so far been bogged down by arguments over the SNC representation and the number of seats the rival groups – which include Islamists, leftists and secularists – will have in a proposed assembly. Seif said he hoped for agreement on that on Thursday night, although the talks may continue into Friday.


Senior SNC member Burhan Ghalioun said the participants were moving towards consensus: “The atmosphere was positive. We all agree that we don’t want to walk away from this meeting in failure,” he told reporters.


Seif’s proposal is the first concerted attempt to merge opposition forces to help end the devastating conflict.


The initiative would also create a Supreme Military Council, a Judicial Committee and a transitional government-in-waiting of technocrats – along the lines of Libya’s Transitional National Council, which managed to galvanize international support for its successful battle to topple Gaddafi.


Michael Doran of the Brookings Institute in Washington told a forum in Doha it would not work for Syria. “It’s not a ridiculous idea, but it’s not going to succeed,” he said.


A diplomat on the sidelines of the talks said international divisions in the U.N. Security council did not help.


“It’s a vicious circle. They are asking the opposition to unite when they admit they are not themselves united,” he said.


(Writing by Tom Perry and Samia Nakhoul; Editing by Alistair Lyon, Alastair Macdonald and Philippa Fletcher)


World News Headlines – Yahoo! News



Read More..

Ghana building collapse traps dozens, kills 1
















ACCRA, Ghana (AP) — A five-story shopping center built earlier this year in a bustling suburb of Ghana‘s capital collapsed Wednesday, killing at least one person and leaving several dozen people trapped in the rubble, authorities and eyewitnesses said.


Rescue crews used cranes to try and remove debris from the top of the building amid fears that machinery sifting through the wreckage could injure trapped survivors. Crowds of bystanders gathered as rescuers sifted through cement and glass.













The fatality at the Melcom Shopping Center at Achimota, a suburb of Accra, was confirmed by Public Affairs Officer of the Ghana Fire Service Billy Anaglate. “We are still working to find out the fate of others who may be trapped under,” he said.


Other officials told The Associated Press that the death toll was likely to rise.


An AP reporter at the scene saw at least one man pulled from the debris, covered in dust and who was then whisked into an ambulance.


A Greater Accra Regional Public Affairs officer, deputy superintendent Freeman Tettey, confirmed that one person died and told the AP that 51 have been rescued and sent to hospitals around the capital.


“I was on my way to the shop when l saw it crumpling down,” Kojo Boadi, an eyewitness, said.


President John Mahama declared the scene a disaster zone and cut short his election campaign in the north of the country to be able to visit the site. The presidential election is scheduled for December.


The five-story store opened in February is part of the Melcom chain owned by Indian immigrant magnate, Bhagwan Khubchandani. His late father arrived in Ghana in 1929 as a 14-year-old to work as a store boy in the-then Gold Coast.


The store sells a variety of cheap, imported household goods and appliances that are popular with working-class Ghanaians.


Africa News Headlines – Yahoo! News



Read More..

Exclusive: Google Ventures beefs up fund size to $300 million a year

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Rihanna a rock star on Victoria’s Secret catwalk
















NEW YORK (AP) — Rihanna rocked lingerie at Wednesday night’s Victoria’s Secret fashion show in New York, providing the highlight of the live-music soundtrack and holding her own on the catwalk with some of the world’s top models.


And those models even had props, including Adriana Lima‘s ringmaster wand, Doutzen Kroes‘ body cage and several pairs of the oversized wings that the retailer has made its signature. It would be a close contest who got the biggest wings: Toni Garrn’s giant poppy pair or Miranda Kerr’s swan-style feathered pouf. Only Lily Aldridge could boast star-spangled wings that shot out silver sparkles.













Alessandra Ambrosio’s orchid-petal wings might have lacked a little grandeur, but she made up for it with a $ 2.5 million jeweled “floral fantasy bra.”


Still, wearing a sheer pink mini that gave glimpses of her bra, Rihanna sang “Fresh Out the Runway” at the end of the corset-and-garter parade and she was the one to grab the audience’s biggest applause.


The fashion show has become a pre-holiday season tradition for the retailer. CBS will turn it into a one-hour special, which also had performances from Justin Bieber and Bruno Mars, to be shown on Dec. 4.


Lima said she loved opening the show in the ringmaster costume. “The atmosphere of the Victoria’s Secret fashion show is electric,” she said. “It’s so much fun to be able to interact with the audience! What other show will you see Rihanna, Justin Beiber and Bruno Mars on the runway with angels?”


This year’s event had a slight twist. It started with an announcer noting that Victoria’s Secret and CBS had each made a donation to relief efforts for Superstorm Sandy, and a thank you to the National Guard members who are based out of the Lexington Avenue Armory that has for years been home to the show.


Mostly, though, models are encouraged to smile, ham it up and show off the extra time at the gym that most admit to in the weeks beforehand. “It’s highly televised, and you take that into consideration,” said model Joan Smalls ahead of the show. “This is kind of not the same as other runways. You have to prepare your body: No. 1 is the wings are heavy, and No. 2 is you have to be comfortable with your body because the camera will pick up on it if you’re not comfortable and confident.”


There’s an emphasis on glitz, skin and dramatic production here, not wearable undergarment trends for typical Victoria’s Secret shoppers. It was divided into six sections: Circus, complete with acrobats, contortionists and a sword eater; Dangerous Liaisons; Pink Is Us; Silver Screen Angels; Angels in Bloom; and Calendar Girls, which allowed Bruno Mars to serenade a model for each month of the year.


For his first song, “Beauty and the Beat,” Bieber, wearing low-slung white pants and a white leather studded vest, sat alone with his guitarist in the mellowest part of the show. For “As Long As You Love Me,” however, he brought in backup dancers and interacted with the models while moving around a giant makeshift pinball machine.


“It’s like a dream come true,” said Bieber on the pink carpet before the show. “I would rather be here than anywhere in the world.”


___


AP reporter John Carucci contributed to this report.


___


Samantha Critchell tweets fashion at http://www.twitter.com/AP_Fashion


Entertainment News Headlines – Yahoo! News



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